The Sooner offense, as in game one and throughout much of the season, was stagnant and couldn't really produce anything to back OU pitching.
On the other side, LSU came up with all the timely hits it needed at all the right times.
Much of that on this night came off the bat of second baseman JaCoby Jones, who finished 4-for-4 and a triple short of the cycle.
In fact, over a span of five plate appearances in the series, Jones hit for the cycle.
His RBI single in the top of the second knotted things up at one apiece after the Sooners took an early 1-0 lead in the first.
The Tigers took their first lead in the third courtesy of a trio of Sooner errors—they committed four on the night.
They added one more each in the fourth, sixth and eighth on right fielder Jared Foster's RBI single, an RBI groundout and Jones' homer to left, respectively.
Then, the big insurance blow and came in the ninth in the form of a six-spot as the wheels starting falling off for OU.
Considering OU's ineptitude offensively, that was infinitely more than what the Tigers needed.
OU's lone run in the first came on center fielder Max White's RBI single to right.
But after that, the Sooners mustered just three hits off LSU pitching, largely a relief effort after starter Ryan Eades exited following a 50 minute lightning delay.
In his final OU outing, OU starter Dillon Overton spanned just 5 2/3 innings while allowing three earned runs on seven hits and a walk in a loss.
He fanned three.
The Sooners lose a number of key guys, including White, Overton and ace Jonathan Gray, but many others will return for a team that hopes to chase a dream of returning to Omaha for the first time since 2010 again.