For just the second time all year, Pledger finished without a 3-point field goal, missing all four of his tries and going just 2-for-7 overall from the field in the game.
And the Sooners collectively shot just 32.7 percent from the field, all the while turning the ball over 16 times to just seven for the Red Raiders.
That contributed to a 25-22 halftime deficit growing much deeper in the second half, when the Red Raiders shot a scorching hot 55.6 percent en route to leading by as much as 20 with just more than a minute remaining.
Tech finished 43.1 percent shooting in the contest.
The one bright spot for OU proved to be forward Andrew Fitzgerald's performance, as he mustered 14 points on 7-for-16 shooting, most in the first half.
OU jumped out to an early 5-0 lead, but it was short lived when the Red Raiders bounced back after not scoring in the first four-plus minutes.
The teams tied once and traded the lead once.
Once the Red Raiders seized it, they never relinquished it again, commanding the game for the entire second half.
Tech won the battle in the paint 28-6 and had 12 points off turnovers to just four for OU.
The Sooners (13-11, 3-9 Big 12) will try to rebound when they face Red River Rival Texas Tuesday at Lloyd Noble Center.